Lupus is a chronic, autoimmune disease caused when the immune system attacks its own tissues. It can affect the joints, skin, kidneys, blood cells, brain, heart, and lungs. Symptoms vary but common ones include fatigue, joint pain, rash, and fever. While there's no cure for lupus, current treatments focus on improving quality of life through controlling symptoms and minimizing flare-ups. It is a relatively common disease, affecting an estimated 1.5 million Americans. A majority of these sufferers are adult women between the ages of 19 and 60.